Case Studies Streamlining Registration and Requests for Gene Editing
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Streamlining Registration and Requests for Gene Editing

Analytics & Modeling - Process Analytics
Application Infrastructure & Middleware - Data Exchange & Integration
Healthcare & Hospitals
Life Sciences
Product Research & Development
Predictive Quality Analytics
Root Cause Analysis & Diagnosis
Data Science Services
Intellia was facing several challenges in their registration and request process for their CRISPR/Cas9-based gene editing therapeutics. The previous registration process was scattered across SharePoint spreadsheets, emails, and paper, leading to unreliable data and a significant amount of time spent piecing together lineages. Their plasmid repositories couldn’t be tracked and kept up to date. Furthermore, the lack of a formal request system led to lost requests and insufficient detail in requests. Without a reliable plasmid inventory, certain requests were difficult to complete.
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Intellia is a company that is developing CRISPR/Cas9-based gene editing therapeutics with in vivo and ex vivo delivery models. They are at the forefront of the gene editing industry, using advanced technology to create therapeutics that can potentially revolutionize the healthcare industry. However, their operations were being hindered by an inefficient and outdated registration and request system.
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To address these challenges, Intellia implemented a centralized registration system. This system uses standardized lists of plasmids and other entities to make data reliable and easily shared. This has significantly improved the reliability of their data and reduced the time spent on registration. In addition, they introduced a streamlined request triaging system. With Request Management, teams can generate greater throughput and higher quality products because they can easily access the information they need. Finally, they implemented Workflow Management to generate R&D insights. This system empowers Intellia to identify the upstream entities that lead to successful batches. For example, they can now answer questions like, “Which bio-vector led to this particularly effective protein batch?”
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Centralized and standardized registration system leading to reliable and easily shared data.
Streamlined request triaging system allowing for greater throughput and higher quality products.
Implementation of Workflow Management to generate R&D insights and identify successful batches.
Increased productivity due to streamlined request triaging.
Improved data reliability due to centralized registration.
Enhanced R&D insights due to Workflow Management.
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