Egnyte Case Studies Nimbus Therapeutics Leverages IoT to Automate CRO Data Ingestion and Accelerate Drug Development
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Nimbus Therapeutics Leverages IoT to Automate CRO Data Ingestion and Accelerate Drug Development

Egnyte
Application Infrastructure & Middleware - Database Management & Storage
Infrastructure as a Service (IaaS) - Public Cloud
Pharmaceuticals
Quality Assurance
Onsite Human Safety Management
Root Cause Analysis & Diagnosis
System Integration
Testing & Certification
Nimbus Therapeutics, a biotech company, was grappling with the challenge of managing increasing volumes of data from multiple experiments and projects. The company's reliance on manual data management processes was proving unsustainable. The team had to validate the data, upload it into the corporate database, reconcile different data formats, and troubleshoot any issues. Human error at any of these steps threatened data integrity. Inefficiency was another challenge as the team had to create a new file or manually update and rename an existing one each time a document was modified. Lack of visibility and accountability was a problem as file update notifications were sent through email, which could easily get lost in crowded inboxes. Stakeholders were dispersed across time zones, which often slowed the process. Content sat for hours or days before the data team started their workday.
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Nimbus Therapeutics is a biotechnology company based in Cambridge, Massachusetts, USA. The company is involved in running multiple experiments and projects simultaneously, generating a large volume of data. The company was heavily reliant on manual processes for data management, which was proving to be inefficient and prone to errors. The company has 77 employees and uses Egnyte's Platform Enterprise for data storage. The company's data management processes involve external vendors and stakeholders dispersed across different time zones.
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Nimbus Therapeutics decided to automate the transfer and management of data. The company was already using Egnyte for data storage. Dr. Carazza, who joined the company in 2018, saw an opportunity to use Egnyte’s built-in public cloud workflows and integrations to automate how content sent from vendor partners was handled. A tech stack was assembled, consisting of Jira™, AWS Lambda, and other platforms, to create an end-to-end solution that would automate how the data was received, validated, uploaded, and updated. Egnyte acted as the hub for the data team to synthesize these tools into a cohesive, interconnected workflow, referred to as NIMBEye. Egnyte facilitated the interconnected use of Lambda (AWS’ event-driven compute service) and Jira’s workflow and ticketing system to accelerate the process of finding new content and getting it into the database. The team now uses several key features in Egnyte, including version control, secure links, issue alerts, and metadata capture.
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The automation of data transfer and management has brought about significant operational benefits for Nimbus Therapeutics. The company has been able to reduce its reliance on manual, human-driven processes by two-thirds, which were more vulnerable to errors and delays. This has also helped combat employee burnout as former members of the team can now focus on higher-value efforts elsewhere in the company’s operations. The data uploading process has been substantially accelerated, with data now being loaded and deployed to end users within 30 minutes of being sent from the CRO. The potential for human error has been virtually eliminated, which has helped preserve data integrity and improve data quality. In a time-sensitive field like drug discovery, it has empowered Nimbus to remove bottlenecks from the process of CRO data ingestion.
Decreased resource needs from 3 full-time employees to 1 part-time employee
Over 99% of data upload cases were fully automated in 2021
71% of data are loaded into the database and viewable within 30 minutes of being uploaded to Egnyte from CRO
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