ANSYS Case Studies Implementing ANSYS FSI Solution for Advanced Cardiology Research at Colorado Health Science Center

	Implementing ANSYS FSI Solution for Advanced Cardiology Research at Colorado Health Science Center ANSYS

Implementing ANSYS FSI Solution for Advanced Cardiology Research at Colorado Health Science Center

ANSYS

Technology Category	Analytics & Modeling - Digital Twin / Simulation Sensors - Level Sensors
Applicable Industries	Healthcare & Hospitals Life Sciences
Applicable Functions	Product Research & Development
Use Cases	Digital Twin Virtual Reality
Challenge	The University of Colorado Health Science Center's cardiology research engineers were seeking to gain a deeper understanding of pulmonary arterial hypertension (PAH), a condition characterized by persistently high pressure in the vessels that transport oxygen-poor blood from the heart's right ventricle to the small arteries in the lungs. Over time, the increased load due to PAH can lead to premature heart failure and death. The current clinical methods for diagnosing and evaluating PAH are invasive and only consider the mean flow rate and pressure drop across the vasculature. The challenge was to simulate transient hemodynamics and arterial motion, which required a solution for the coupled solid and fluid domains. The geometry definition was derived from medical imaging, and the constitutive modeling of the vasculature was complex due to hyperelastic materials and complex constraint relationships. Additionally, the fluid boundary conditions could not be simply characterized. Read More
About Customer	The University of Colorado Health Science Center is a leading institution in the field of biomedical research in the United States. The center's cardiology research engineers are dedicated to advancing the basic knowledge of diseases and developing new disease diagnostics. They use mechanics-based models of varying complexity to gain insights into various diseases, including pulmonary arterial hypertension (PAH). Their work is critical in understanding the progression of PAH and improving predictions of potential treatment outcomes. Read More
Solution	The ANSYS FSI Solution was implemented to provide a complete solution for the coupled simulation of fluid structure interaction. ANSYS® ICEM CFD™ Hexa was used to provide high-quality quad and hex element shell and volume meshes for geometries determined from imaging data. The ANSYS FEA solid modeling capabilities allowed for the definition of hyperelastic material models and complex constraint equations. ANSYS CFX provided a robust CFD solver coupled with FEA and key features such as an expression language that allowed for the definition of various physiological boundary conditions. This comprehensive solution enabled the researchers to gain a better understanding of the transient physics involved in PAH and insight into the effects of vascular stiffness. Read More Log in to view content
Contents

Technology Category

Analytics & Modeling - Digital Twin / Simulation

Sensors - Level Sensors

Applicable Industries

Healthcare & Hospitals

Life Sciences

Applicable Functions

Product Research & Development

Use Cases

Digital Twin

Virtual Reality

Challenge

The University of Colorado Health Science Center's cardiology research engineers were seeking to gain a deeper understanding of pulmonary arterial hypertension (PAH), a condition characterized by persistently high pressure in the vessels that transport oxygen-poor blood from the heart's right ventricle to the small arteries in the lungs. Over time, the increased load due to PAH can lead to premature heart failure and death. The current clinical methods for diagnosing and evaluating PAH are invasive and only consider the mean flow rate and pressure drop across the vasculature. The challenge was to simulate transient hemodynamics and arterial motion, which required a solution for the coupled solid and fluid domains. The geometry definition was derived from medical imaging, and the constitutive modeling of the vasculature was complex due to hyperelastic materials and complex constraint relationships. Additionally, the fluid boundary conditions could not be simply characterized.

About Customer

The University of Colorado Health Science Center is a leading institution in the field of biomedical research in the United States. The center's cardiology research engineers are dedicated to advancing the basic knowledge of diseases and developing new disease diagnostics. They use mechanics-based models of varying complexity to gain insights into various diseases, including pulmonary arterial hypertension (PAH). Their work is critical in understanding the progression of PAH and improving predictions of potential treatment outcomes.

Solution

The ANSYS FSI Solution was implemented to provide a complete solution for the coupled simulation of fluid structure interaction. ANSYS® ICEM CFD™ Hexa was used to provide high-quality quad and hex element shell and volume meshes for geometries determined from imaging data. The ANSYS FEA solid modeling capabilities allowed for the definition of hyperelastic material models and complex constraint equations. ANSYS CFX provided a robust CFD solver coupled with FEA and key features such as an expression language that allowed for the definition of various physiological boundary conditions. This comprehensive solution enabled the researchers to gain a better understanding of the transient physics involved in PAH and insight into the effects of vascular stiffness.

Impact #1	The implementation of the ANSYS FSI Solution has shown promising results in the preliminary studies, demonstrating the feasibility of FSI simulation of transient hemodynamics. This has allowed researchers to gain a better understanding of the transient physics involved in PAH and insight into the effects of vascular stiffness. Upcoming studies with improved clinical and imaging data will allow for further validation and refinement of the simulation methodology. Ultimately, the clinical use of non-invasive patient-specific simulation may provide a better understanding of the progression of PAH and improved predictions of potential treatment outcomes.

Impact #1

The implementation of the ANSYS FSI Solution has shown promising results in the preliminary studies, demonstrating the feasibility of FSI simulation of transient hemodynamics. This has allowed researchers to gain a better understanding of the transient physics involved in PAH and insight into the effects of vascular stiffness. Upcoming studies with improved clinical and imaging data will allow for further validation and refinement of the simulation methodology. Ultimately, the clinical use of non-invasive patient-specific simulation may provide a better understanding of the progression of PAH and improved predictions of potential treatment outcomes.

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Overview

Implementing ANSYS FSI Solution for Advanced Cardiology Research at Colorado Health Science Center

Operational Impact