Case Studies Cue Biopharma & Benchling: Evolving into a clinical-stage organization

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	Cue Biopharma & Benchling: Evolving into a clinical-stage organization

Cue Biopharma & Benchling: Evolving into a clinical-stage organization

Technology Category	Platform as a Service (PaaS) - Data Management Platforms
Applicable Industries	Healthcare & Hospitals Life Sciences
Applicable Functions	Product Research & Development Quality Assurance
Use Cases	Inventory Management Predictive Maintenance
Services	Cloud Planning, Design & Implementation Services Data Science Services
Challenge	Cue Biopharma, a company that designs novel biologics to modify the immune system to fight diseases, was transitioning from a research-centric organization to a clinical-stage organization. This transition involved bringing early development activities in-house to achieve greater control over the types and quality of work done by their teams. However, they faced challenges with non-standardized data capture, barriers to communication and handoffs between teams, and the need for a digital infrastructure to support their growth. They were using shared spreadsheets to manage information, which posed risks such as unintended edits and duplicates. As the company tripled in size, it became increasingly difficult for key pieces of information to efficiently flow through the organization. Read More
About Customer	Cue Biopharma is a biopharmaceutical company that is engineering a novel class of injectable biologics to selectively engage and modulate targeted T cells directly within the patient’s body. Their approach aims to transform the treatment of cancer, infectious disease, and autoimmune disease by leveraging a natural immune response with innovative protein engineering. This approach aims to achieve a more controlled immune response, providing greater patient benefit while reducing toxicity. The company is based in Cambridge, MA, and has between 50 to 100 employees. In a push to move new safe and efficacious immunotherapies to patients, Cue Biopharma has scaled and grown into a clinical-stage company by expanding its development work in-house. Read More
Solution	Cue Biopharma utilized Benchling as their unified cloud solution to establish the data management infrastructure required for their work and establish a bidirectional flow of information between the Research and Development groups. Samantha Povlich, a Principal Scientist and Head of Analytical Outsourcing and Stability at Cue Biopharma, built a data model within Benchling that stored the name, location, history, and results of all samples in an interconnected suite of applications. This increased the throughput of information shared between scientists within and across teams, making tracking much more robust and knowledge transfer much more efficient. Samantha also created templates to empower scientists to input all experiment-relevant information into this newly centralized system. Benchling also enabled Cue Biopharma to design a request system to accommodate all testing that happens with all the different permutations of candidate molecules. Read More Log in to view content
Contents

Technology Category

Platform as a Service (PaaS) - Data Management Platforms

Applicable Industries

Healthcare & Hospitals

Life Sciences

Applicable Functions

Product Research & Development

Quality Assurance

Use Cases

Inventory Management

Predictive Maintenance

Services

Cloud Planning, Design & Implementation Services

Data Science Services

Challenge

Cue Biopharma, a company that designs novel biologics to modify the immune system to fight diseases, was transitioning from a research-centric organization to a clinical-stage organization. This transition involved bringing early development activities in-house to achieve greater control over the types and quality of work done by their teams. However, they faced challenges with non-standardized data capture, barriers to communication and handoffs between teams, and the need for a digital infrastructure to support their growth. They were using shared spreadsheets to manage information, which posed risks such as unintended edits and duplicates. As the company tripled in size, it became increasingly difficult for key pieces of information to efficiently flow through the organization.

About Customer

Cue Biopharma is a biopharmaceutical company that is engineering a novel class of injectable biologics to selectively engage and modulate targeted T cells directly within the patient’s body. Their approach aims to transform the treatment of cancer, infectious disease, and autoimmune disease by leveraging a natural immune response with innovative protein engineering. This approach aims to achieve a more controlled immune response, providing greater patient benefit while reducing toxicity. The company is based in Cambridge, MA, and has between 50 to 100 employees. In a push to move new safe and efficacious immunotherapies to patients, Cue Biopharma has scaled and grown into a clinical-stage company by expanding its development work in-house.

Solution

Cue Biopharma utilized Benchling as their unified cloud solution to establish the data management infrastructure required for their work and establish a bidirectional flow of information between the Research and Development groups. Samantha Povlich, a Principal Scientist and Head of Analytical Outsourcing and Stability at Cue Biopharma, built a data model within Benchling that stored the name, location, history, and results of all samples in an interconnected suite of applications. This increased the throughput of information shared between scientists within and across teams, making tracking much more robust and knowledge transfer much more efficient. Samantha also created templates to empower scientists to input all experiment-relevant information into this newly centralized system. Benchling also enabled Cue Biopharma to design a request system to accommodate all testing that happens with all the different permutations of candidate molecules.

Impact #1	Consistent, structured data capture in templates allowed deeper insights to be drawn across experiments.
Impact #2	Collaboration and handoffs between teams — particularly between research and development — are efficient and effortless.
Impact #3	Cue Biopharma is clinical-stage ready and has a 360-degree view of scientific progress driving outcomes.

Impact #1

Consistent, structured data capture in templates allowed deeper insights to be drawn across experiments.

Impact #2

Collaboration and handoffs between teams — particularly between research and development — are efficient and effortless.

Impact #3

Cue Biopharma is clinical-stage ready and has a 360-degree view of scientific progress driving outcomes.

Benefit #1	Cue Biopharma now records over 90% of their experiments using a template.

Benefit #1

Cue Biopharma now records over 90% of their experiments using a template.

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Overview

Cue Biopharma & Benchling: Evolving into a clinical-stage organization

Operational Impact

Quantitative Benefit