Case Studies CSIRO BioFoundry and TeselaGen Collaboration
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CSIRO BioFoundry and TeselaGen Collaboration

Analytics & Modeling - Predictive Analytics
Functional Applications - Remote Monitoring & Control Systems
Life Sciences
Healthcare & Hospitals
Pharmaceuticals
Product Research & Development
Process Manufacturing
Quality Assurance
Predictive Maintenance
Machine Condition Monitoring
Remote Asset Management
System Integration
Software Design & Engineering Services
Training
The CSIRO BioFoundry faced several challenges in integrating automation equipment with a Laboratory Information Management System (LIMS). They needed to explore a larger number of designs simultaneously, track items and changes in the state of samples, and reduce the time required to identify candidate strains successfully. Additionally, they required a system capable of generating and executing workflows while storing both phenotypic and genotypic data. These challenges necessitated a robust software infrastructure to support their high-throughput processes and machinery.
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The CSIRO BioFoundry is a leading facility in the field of synthetic biology, applying engineering principles to biology. Specializing in high-volume design and build services, the BioFoundry's equipment allows users to perform full workflows, including combinatorial genetic design and high-throughput genetic strain build. Their capabilities are powered by a suite of robotics for DNA assembly and transformation, extending to basic phenotyping and linking to metabolomics, protein production, and other facilities within CSIRO. The BioFoundry serves as a hub for the synthetic biology community, industry, and the research and development ecosystem, envisioned as a focal point of cutting-edge technology.
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TeselaGen provided the CSIRO BioFoundry with a comprehensive software infrastructure through its DESIGN and BUILD modules, along with a powerful Laboratory Information Management System (LIMS). The DESIGN module enabled scientists to design constructs and organisms in batch, facilitating advanced combinatorial and hierarchical designs. The BUILD module allowed for the planning, generation, and execution of workflows, including the generation of plate maps and integration with automation equipment. TeselaGen's software also provided access to parts and plasmids databases, supporting the BioFoundry's high-throughput experimental needs. Additionally, the software's robust search engine allowed users to trace items and changes in the state of samples effectively.
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TeselaGen's software achieved 100% integration with the automation equipment used by the CSIRO BioFoundry.
The BUILD module facilitated the planning, generation, and execution of workflows, including the generation of plate maps and integration with automation equipment.
Users expressed satisfaction with TeselaGen's ability to trace items and changes in the state of samples through its powerful search engine.
CSIRO witnessed a 2 to 10 times reduction in reagent use with TeselaGen as its software backbone.
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