Case Studies Accelerating Synthetic Biology with Fully Unified Informatics

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	Accelerating Synthetic Biology with Fully Unified Informatics

Accelerating Synthetic Biology with Fully Unified Informatics

Technology Category	Platform as a Service (PaaS) - Data Management Platforms
Applicable Industries	Healthcare & Hospitals Life Sciences
Applicable Functions	Product Research & Development
Use Cases	Predictive Quality Analytics Regulatory Compliance Monitoring
Services	Data Science Services
Challenge	Synlogic, a company developing microbe-based therapeutics, faced several challenges in their operations. Their complex workflows were being sketched out step-by-step on paper, which hindered collaboration and reproducibility. Without a workflow system linked to a registration system, it was difficult for Synlogic to trace the lineages of their candidates. Additionally, placing requests, uploading results from instruments, and collating data across experiments were cumbersome and unreliable without unified, intelligent systems. Read More
About Customer	Synlogic is a pioneering company in the field of synthetic biology, developing microbe-based therapeutics to treat a wide array of diseases. These diseases range from cancer to genetic inborn errors of metabolism. The company's innovative approach to therapeutics involves leveraging the natural capabilities of microbes to produce and deliver therapeutics in the body. However, the complexity of their work and the need for precise tracking and data management presented significant challenges. Read More
Solution	To address these challenges, Synlogic turned to Benchling, a unified informatics platform. Benchling developed a custom data model that maps to Synlogic’s unique workflows, enabling real-time experiment tracking and automating lineage tracking. This solution provided a much-needed structure to Synlogic's complex workflows and made it easier to trace the lineages of their candidates. Additionally, Benchling integrated Synlogic's instruments with the informatics requests system and bioreactors. This integration streamlined the process of placing requests and automatically associated results data with samples. As a result, Synlogic was able to streamline their IND filing process by using Benchling links in IND filings to provide full experimental history. Read More Log in to view content
Contents

Technology Category

Platform as a Service (PaaS) - Data Management Platforms

Applicable Industries

Healthcare & Hospitals

Life Sciences

Applicable Functions

Product Research & Development

Use Cases

Predictive Quality Analytics

Regulatory Compliance Monitoring

Services

Data Science Services

Challenge

Synlogic, a company developing microbe-based therapeutics, faced several challenges in their operations. Their complex workflows were being sketched out step-by-step on paper, which hindered collaboration and reproducibility. Without a workflow system linked to a registration system, it was difficult for Synlogic to trace the lineages of their candidates. Additionally, placing requests, uploading results from instruments, and collating data across experiments were cumbersome and unreliable without unified, intelligent systems.

About Customer

Synlogic is a pioneering company in the field of synthetic biology, developing microbe-based therapeutics to treat a wide array of diseases. These diseases range from cancer to genetic inborn errors of metabolism. The company's innovative approach to therapeutics involves leveraging the natural capabilities of microbes to produce and deliver therapeutics in the body. However, the complexity of their work and the need for precise tracking and data management presented significant challenges.

Solution

To address these challenges, Synlogic turned to Benchling, a unified informatics platform. Benchling developed a custom data model that maps to Synlogic’s unique workflows, enabling real-time experiment tracking and automating lineage tracking. This solution provided a much-needed structure to Synlogic's complex workflows and made it easier to trace the lineages of their candidates. Additionally, Benchling integrated Synlogic's instruments with the informatics requests system and bioreactors. This integration streamlined the process of placing requests and automatically associated results data with samples. As a result, Synlogic was able to streamline their IND filing process by using Benchling links in IND filings to provide full experimental history.

Impact #1	Improved collaboration and reproducibility through the use of a unified informatics platform.
Impact #2	Enhanced traceability of candidate lineages through automated lineage tracking.
Impact #3	Streamlined request placement and data collation through integrated systems.

Impact #1

Improved collaboration and reproducibility through the use of a unified informatics platform.

Impact #2

Enhanced traceability of candidate lineages through automated lineage tracking.

Impact #3

Streamlined request placement and data collation through integrated systems.

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Overview

Accelerating Synthetic Biology with Fully Unified Informatics

Operational Impact