DataDirect Networks Case Studies ACCELERATE: LIFE SCIENCES - Racing to Find a Cure, TGEN Uses DDN® Storage to Unravel the Genetic Components of Disease, Faster

Edit This Case Study Record

	ACCELERATE: LIFE SCIENCES - Racing to Find a Cure, TGEN Uses DDN® Storage to Unravel the Genetic Components of Disease, Faster DataDirect Networks

ACCELERATE: LIFE SCIENCES - Racing to Find a Cure, TGEN Uses DDN® Storage to Unravel the Genetic Components of Disease, Faster

DataDirect Networks

Technology Category	Infrastructure as a Service (IaaS) - Cloud Storage Services Infrastructure as a Service (IaaS) - Hybrid Cloud
Applicable Industries	Healthcare & Hospitals Life Sciences
Applicable Functions	Product Research & Development
Use Cases	Edge Computing & Edge Intelligence Predictive Maintenance
Services	Cloud Planning, Design & Implementation Services System Integration
Challenge	TGen, a leading genomics research institute, was facing challenges with its legacy NAS system which was underpowered and unable to handle concurrent jobs without dragging performance below acceptable levels. Scaling NAS performance was expensive and time-consuming. Moreover, data growth was accelerating, making the existing infrastructure untenable. Genomics, the art of extracting understanding from an organism’s genome, is a complex and data-intensive task. The year-on-year improvements, in volume and accuracy of data being generated by gene sequencing instruments are mind-boggling. As these machines become more productive, the price for gene sequencing, assembly, and analysis drops, enabling new diagnostic methods and disease treatments. However, all this genetic data has resulted in a sea change in how to assemble them into meaningful data, so the analysis can take place. Read More
About Customer	The Translational Genomics Research Institute (TGen) is a leading genomics research institute focused on developing early diagnostics and effective treatment strategies through the understanding and application of genetics. By leveraging state-of-the-art genomic sequencing technology, TGen is at the forefront of understanding the underlying biological effects that are at the root of a broad range of human diseases and disorders. Since its inception, TGen’s mission has been to use genetics to drive decisions and innovations to prevent, diagnose, and treat disease. Since 2002, TGen’s IT department has been accelerating the discovery process by leveraging new innovative technologies and methods for its user community. Read More
Solution	TGen approached Arizona State University Advance Computing Center (A2C2) to collaborate on a best-in-class HPC platform that would address the needs of the University and TGen. The solution was based on a legacy HPC system, coined Saguaro which today consists of over 5,000 processor cores delivering more than 40 teraflops of computation power, a 400TB EXAScaler Lustre scratch space based the SFA12K-40™ Storage Engine, 11 Terabytes of aggregate RAM, 1.5 Giga-bytes of aggregate L2 cache, and a Double fat tree DDR InfiniBand network. By deploying EXAScaler at A2C2, and leveraging a 10 Gigabit network interface between the two facilities, TGen was able to eliminate the assembly bottleneck imposed by their legacy clustered NAS/NFS system. TGEN and ASU now have in place a scalable, high-performance storage solution for both today’s and tomorrows’ research. Read More Log in to view content
Contents

Technology Category

Infrastructure as a Service (IaaS) - Cloud Storage Services

Infrastructure as a Service (IaaS) - Hybrid Cloud

Applicable Industries

Healthcare & Hospitals

Life Sciences

Applicable Functions

Product Research & Development

Use Cases

Edge Computing & Edge Intelligence

Predictive Maintenance

Services

Cloud Planning, Design & Implementation Services

System Integration

Challenge

TGen, a leading genomics research institute, was facing challenges with its legacy NAS system which was underpowered and unable to handle concurrent jobs without dragging performance below acceptable levels. Scaling NAS performance was expensive and time-consuming. Moreover, data growth was accelerating, making the existing infrastructure untenable. Genomics, the art of extracting understanding from an organism’s genome, is a complex and data-intensive task. The year-on-year improvements, in volume and accuracy of data being generated by gene sequencing instruments are mind-boggling. As these machines become more productive, the price for gene sequencing, assembly, and analysis drops, enabling new diagnostic methods and disease treatments. However, all this genetic data has resulted in a sea change in how to assemble them into meaningful data, so the analysis can take place.

About Customer

The Translational Genomics Research Institute (TGen) is a leading genomics research institute focused on developing early diagnostics and effective treatment strategies through the understanding and application of genetics. By leveraging state-of-the-art genomic sequencing technology, TGen is at the forefront of understanding the underlying biological effects that are at the root of a broad range of human diseases and disorders. Since its inception, TGen’s mission has been to use genetics to drive decisions and innovations to prevent, diagnose, and treat disease. Since 2002, TGen’s IT department has been accelerating the discovery process by leveraging new innovative technologies and methods for its user community.

Solution

TGen approached Arizona State University Advance Computing Center (A2C2) to collaborate on a best-in-class HPC platform that would address the needs of the University and TGen. The solution was based on a legacy HPC system, coined Saguaro which today consists of over 5,000 processor cores delivering more than 40 teraflops of computation power, a 400TB EXAScaler Lustre scratch space based the SFA12K-40™ Storage Engine, 11 Terabytes of aggregate RAM, 1.5 Giga-bytes of aggregate L2 cache, and a Double fat tree DDR InfiniBand network. By deploying EXAScaler at A2C2, and leveraging a 10 Gigabit network interface between the two facilities, TGen was able to eliminate the assembly bottleneck imposed by their legacy clustered NAS/NFS system. TGEN and ASU now have in place a scalable, high-performance storage solution for both today’s and tomorrows’ research.

Impact #1	DDN EXAScaler eliminated network access bottlenecks, delivering the power for concurrent jobs today and in the future.
Impact #2	EXAScaler capacity costs decrease as it scales. Multiple EXAScalers can be added under a single Lustre File system for continued long term, low cost growth.
Impact #3	An infrastructure that scales easily as science accelerates– allowing them to focus on translational research, not computer design.

Impact #1

DDN EXAScaler eliminated network access bottlenecks, delivering the power for concurrent jobs today and in the future.

Impact #2

EXAScaler capacity costs decrease as it scales. Multiple EXAScalers can be added under a single Lustre File system for continued long term, low cost growth.

Impact #3

An infrastructure that scales easily as science accelerates– allowing them to focus on translational research, not computer design.

Download PDF Version

Overview

ACCELERATE: LIFE SCIENCES - Racing to Find a Cure, TGEN Uses DDN® Storage to Unravel the Genetic Components of Disease, Faster

Operational Impact